| 产品详情 |
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| Antigenic Specificity | ARFGEF2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ARFGEF2 Polyclonal Antibody. Guanine nucleotide-exchange proteins (GEPs) accelerate replacement of bound GDP with GTP and thereby activate ADP-ribosylation factors (ARFs), a family of guanine nucleotide-binding proteins that play an important role in intracellular vesicular trafficking. GEPs comprise two major families, large GEPs that are inhibited by brefeldin A (BFA), a protein that effects golgi structure, and a group of smaller GEPs that are insenstive to BFA. Two genes for GEPs found on human chromosomes 8 and 20 encode BFA sensitive GEPs of approximately 200 kDa, designated BIG1 and BIG2. Both GEPS contain a sec7 domain that is responsible for their brefeldin inhibition and also their catalytic activity. In vivo, BIG1 and BIG2 exist |
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| Immunogen | n/a |
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| Other Names | Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Brefeldin A-inhibited GEP 2; ADP-ribosylation factor guanine nucleotide-exchange factor 2; ARFGEF2; ARFGEP2; BIG2 |
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| Gene, Accession # | Entrez: 10564, 296380, 99371; Uniprot: A2A5R2, Q7TSU1, Q9Y6D5 |
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| Catalog # | PA5-75390 |
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| Price | |
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| Order / More Info | ARFGEF2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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