| 产品详情 |
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| Antigenic Specificity | PTPN14 |
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| Clone | T40-AF7C8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PTPN14 Monoclonal Antibody (T40-AF7C8). Protein-tyrosine phosphatase 14 (PTPN14/PTPD2/PEZ) is a 130kDa multidomain cytosolic protein, and belongs to the NT6 subtype of PTPs. It is characterized by an N-terminal FERM domain (Band 4.1, ezrin, radixin, moesin homology) and a C-terminal PTP domain. Pez (Phosphatase with ezrin domain) may play a role in regulating endothelial cell proliferation during vascular injury and angiogenesis. B-Catenin, a central component of adherens junctions, has been identified as a PTPN14 substrate. TGF, which inhibits cell proliferation but not migration, also inhibits translocation of PTPN14 from the cytosol to the nucleus. |
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| Immunogen | n/a |
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| Other Names | PTP36; cytoskeletal-associated protein tyrosine phosphatase; protein-tyrosine phosphatase pez; tyrosine-protein phosphatase non-receptor type 14 |
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| Gene, Accession # | Entrez: 5784; Uniprot: Q15678 |
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| Catalog # | MA5-17244 |
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| Price | |
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| Order / More Info | PTPN14 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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