| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | NTHL1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 200 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:800, Immunofluorescence: 1:800, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 1:500 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | NTHL1 Polyclonal Antibody. Oxygen radicals damage chromosonal DNA causing cell death and inducing mutations. Although a major focus of oxidatively damaged DNA has centered on the repair of 8-oxo-G, a number of other damaged DNA sites are created by free-radical attack on DNA. The human NTH1 repair protein is one enzyme that has been shown to act on a large number of these other oxidatively damaged DNA sites.A homologue of E. coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity. The NTH protein has broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines. Research indicates NTH plays a crucial role in removal of oxidative base lesions in mitochondrial DNA. |
|---|
| Immunogen | n/a |
|---|
| Other Names | Endonuclease III like 1, NTHL 1, OCTS 3 |
|---|
| Gene, Accession # | Entrez: 18207, 29541, 4913; Uniprot: O35980, P78549 |
|---|
| Catalog # | PA1-16506 |
|---|
| Price | |
|---|
| Order / More Info | NTHL1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|