| 产品详情 |
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| Antigenic Specificity | NTN1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, feline, human, mouse, nonhuman primate, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NTN1 Polyclonal Antibody. Netrin 1's main receptor is DCC (deleted in colorectal cancer- a putative tumor suppressor gene whose expression is lost in numerous cancers). DCC belongs to the so-called family of dependence receptors. These receptors induce apoptosis when their ligand is absent, thus conferring a state of cellular dependence on Netrin 1 availability. The DCC/netrin-1 duo regulates neuron survival during nervous system development. The mechanism(s) by which Netrin 1/ DCC triggers cell death are still unknown. The localization of DCC to lipid rafts appears to be a prerequisite for its proapoptotic activity. |
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| Immunogen | n/a |
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| Other Names | NTN1L |
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| Gene, Accession # | Entrez: 101082606, 114523, 18208, 522767, 9423; Uniprot: O09118, O95631, Q924Z9 |
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| Catalog # | PA1-12869 |
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| Price | |
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| Order / More Info | NTN1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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