| 产品详情 |
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| Antigenic Specificity | ZNRF1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, guinea pig, human, mouse, rabbit, rat, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 0.2-1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ZNRF1 Polyclonal Antibody. E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes neurodegeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons (Probable). |
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| Immunogen | n/a |
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| Other Names | zinc and ring finger 1, B830022L21Rik, MGC101991, Rnf42, Zrfp1, nin283, E3 ubiquitin-protein ligase ZNRF1, nerve injury-induced gene 283 protein, peripheral nerve injury protein nin283, ring finger protein 42, zinc ring finger protein 1 |
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| Gene, Accession # | Entrez: 100349827, 100730744, 170737, 393844, 509076, 690769, 84937; Uniprot: F1MM41, Q6P4U6, Q8ND25, Q91V17 |
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| Catalog # | PA5-69035 |
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| Price | |
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| Order / More Info | ZNRF1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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