| 产品详情 |
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| Antigenic Specificity | ZO-1 |
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| Clone | R26.4C |
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| Host Species | Rat |
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| Reactive Species | canine, mouse, rat |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Immunohistochemistry (Frozen): 10 µg/mL, Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ZO-1 Monoclonal Antibody (R26.4C), eBioscience™. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript varia |
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| Immunogen | n/a |
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| Other Names | DKFZp686M05161, MGC133289, ZO-1 |
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| Gene, Accession # | Entrez: 21872, 292994, 403752; Uniprot: O97758, P39447 |
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| Catalog # | 14-9776-80 |
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| Price | |
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| Order / More Info | ZO-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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