| 产品详情 |
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| Antigenic Specificity | ZO-1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | canine, human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 2.5 µg/mL, Immunohistochemistry (Frozen): Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ZO-1 Polyclonal Antibody. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoform |
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| Immunogen | n/a |
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| Other Names | ZO-1, tight junction protein ZO-1, zona occludens 1, zona occludens protein 1, zonula occludens 1 protein, zonula occludens protein 1 |
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| Gene, Accession # | Entrez: 21872, 292994, 403752, 7082; Uniprot: O97758, P39447, Q07157 |
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| Catalog # | 40-2200 |
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| Price | |
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| Order / More Info | ZO-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16045494, 17210245, 17846148, 17853450, 18552836, 18757308, 19891526, 20360994, 20552673, 21152390, 21350012, 21429969, 21492152, 21559520, 21617913, 21624488, 21717373, 21852400, 21903671, 21969379, 22287976, 22291907, 22292127, 22327832, 22427845, 22509281, 22705477, 22737109, 22819137, 22895806, 23095816, 23213408, 23351752, 23399832, 23553870, 23615438, 23621521, 23675413, 23675446, 24075061, 24166498, 24454736, 24505380, 24535401, 24691741, 24695541, 24895994, 25003755, 25043620, 25108225, 25187991, 25344575, 25513955, 25540130, 25597427, 25763638, 25894862, 25948584, 25991857, 26024086, 26109091, 26109581, 26115671, 26130757, 26182056, 26203142, 26272951, 26379091, 26411364, 26417608, 26518252, 26678431, 26700954, 26772200, 26808080, 26829325, 26885895, 26974005, 26999717, 27008885, 27009841, 27012662, 27023710, 27040283, 27081925, 27097562, 27142375, 27151939, 27167492, 27176222, 27229483, 27278299, 27281269, 27285761, 27380321, 27381832, 27403660, 27478484, 27583194, 27600198, 27605665, 27641813, 27656108, 27659202, 27660200, 27733124, 27748912, 27758134, 27893847, 27926756, 27993979, 28034921, 28103316, 28117276, 28212524, 28233843, 28332063, 28358917, 28713327, 28774343, 28822114, 28861400, 28912466, 29338041, 29508172 |
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