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Antigenic Specificity | ZO-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | canine, guinea pig, human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay Dependent, Immunocytochemistry: 5-10 µg/mL, Immunofluorescence: 5-10 µg/mL, Immunohistochemistry: 2-5 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 0.5-2 µg/mL |
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Description | ZO-1 Polyclonal Antibody. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoform |
Immunogen | n/a |
Other Names | ZO-1, tight junction protein ZO-1, zona occludens 1, zona occludens protein 1, zonula occludens 1 protein, zonula occludens protein 1 |
Gene, Accession # | Entrez: 100718142, 21872, 292994, 403752, 7082; Uniprot: O97758, P39447, Q07157 |
Catalog # | 61-7300 |
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Order / More Info | ZO-1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10559001, 10564641, 10613913, 10712504, 10793144, 10887180, 10992512, 11005751, 11073823, 11179069, 11431439, 11466322, 11470825, 11696560, 11710912, 11711218, 11733531, 11790801, 11880258, 11958524, 11987548, 12136265, 12172645, 12205082, 12403818, 12495220, 12500902, 12538770, 12547828, 12577316, 12633933, 12717711, 12727824, 12808048, 12826663, 12909588, 12932229, 13129853, 14528017, 14593119, 14613887, 14634132, 14685273, 14709721, 14736813, 14744914, 15054114, 15068973, 15084245, 15090040, 15091400, 15194440, 15205571, 15292221, 15327539, 15358599, 15454572, 15494377, 15537864, 15557217, 15558297, 15625121, 15634758, 15691870, 15741167, 15880438, 15917476, 15955087, 15980240, 15980428, 16027150, 16045494, 16127426, 16131493, 16143130, 16185277, 16186252, 16195341, 16267237, 16285205, 16387471, 16436595, 16508790, 16650609, 16678988, 16846040, 16877014, 16909128, 16941028, 16944923, 16957815, 16982627, 16988061, 17015620, 17064680, 17138661, 17202424, 17300235, 17332497, 17347813, 17374535, 17435047, 17460259, 17475869, 17533168, 17636013, 17656471, 17681699, 17699569, 17713529, 17803652, 17899156, 17922819, 17959386, 18075303, 18092342, 18097951, 18162134, 18202193, 18335464, 18355638, 18386163, 18391515, 18417570, 18423437, 18463241, 18508048, 18629939, 18650780, 18927609, 18948813, 18951463, 18973575, 19002577, 19071104, 19093037, 19095767, 19237554, 19240116, 19279126, 19289138, 19373231, 19439447, 19473988, 19497385, 19528242, 19541809, 19584305, 19605546, 19605689, 19656802, 19706291, 19720156, 19787450, 19805521, 19817758, 19828778, 19835853, 19853238, 19997118, 20081189, 20100467, 20109100, 20127760, 20133632, 20135359, 20154215, 20164436, 20181838, 20351147, 20357222, 20398222, 20435084, 20505164, 20505729, 20520761, 20554518, 20604955, 20653957, 20713173, 20880316, 20881963, 20945374, 21038445, 21082384, 21131473, 21186337, 21191089, 21219994, 21305058, 21338320, 21364967, 21364989, 21411628, 21435444, 21471187, 21473743, 21501651, 21514438, 21520040, 21603979, 21849772, 21926108, 21966399, 21967897, 21983942, 22020048, 22028221, 22031541, 22064711, 22144466, 22183388, 22200438, 22218895, 22346733, 22355251, 22384261, 22410172, 22455314, 22463716, 22465559, 22506771, 22615994, 22689949, 22737109, 22748014, 22782886, 22795370, 22797892, 22819675, 22844464, 22868911, 22875787, 22896632, 22926762, 22946046, 22975380, 22994974, 23034938, 23038259, 23136431, 23144919, 23169788, 23220033, 23247886, 23248769, 23255559, 23283995, 23345591, 23357502, 23391266, 23391392, 23403943, 23429425, 23451207, 23467907, 23469079, 23493068, 23518924, 23525011, 23546604, 23554480, 23565266, 23570913, 23631675, 23643492, 23648482, 23649873, 23665760, 23690579, 23723167, 23729595, 23741282, 23831638, 23876515, 23885308, 23910048, 23958315, 24000064, 24106119, 24114543, 24116027, 24169556, 24225006, 24240476, 24259506, 24260326, 24264049, 24273043, 24340021, 24356096, 24443353, 24458021, 24497581, 24510882, 24532171, 24535401, 24550211, 24553072, 24575327, 24584604, 24641494, 24659781, 24768095, 24801942, 24909426, 24932525, 24986862, 24997360, 25014440, 25019507, 25052094, 25070955, 25079037, 25080573, 25082076, 25091940, 25107608, 25136316, 25149679, 25159326, 25217631, 25233349, 25264329, 25291178, 25297509, 25318952, 25340442, 25346532, 25352748, 25386233, 25396731, 25411471, 25448064, 25456071, 25470344, 25486565, 25500882, 25510908, 25545457, 25546475, 25566876, 25593512, 25627141, 25636658, 25640818, 25681460, 25687164, 25689256, 25712527, 25717188, 25726101, 25728352, 25757751, 25777294, 25782021, 25782989, 25812522, 25815897, 25818415, 25893378, 25896246, 25947135, 25948832, 25961453, 26001768, 26048141, 26074069, 26078119, 26078353, 26092209, 26102296, 26157010, 26232046, 26241648, 26246240, 26256764, 26272756, 26272915, 26277777, 26356851, 26368311, 26376988, 26404781, 26441079, 26453937, 26487268, 26501191, 26537751, 26573292, 26635529, 26648273, 26663564, 26678449, 26689643, 26735170, 26771609, 26772142, 26801567, 26812160, 26833402, 26858899, 26861869, 26870320, 26879129, 26887441, 26888480, 26908839, 26913567, 26928868, 26951793, 26958843, 26978024, 26985677, 26990065, 26990447, 27020249, 27020567, 27037276, 27038654, 27040773, 27044745, 27054554, 27121032, 27152411, 27158358, 27179074, 27227787, 27229120, 27286263, 27336173, 27358069, 27385038, 27390776, 27436542, 27463018, 27466317, 27543060, 27633994, 27715411, 27808256, 27815338, 27818230, 27869310, 27939690, 27994454, 28025795, 28035042, 28085667, 28087417, 28251923, 28282420, 28287613, 28293718, 28298893, 28346613, 28356702, 28396408, 28418928, 28508859, 28512143, 28627704, 28701694, 28706260, 28765543, 28811823, 28919709, 28953884, 29179463, 29311781, 29459695, 29487356, 7682777, 8395056, 8855257, 9175707, 9531559, 9990071 |
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