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| Product Name | Recombinant Mouse C-C motif chemokine 12 protein (Ccl12) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 21.78kDa. Partial: 26-221aa. C-terminal 6xHis-tagged. Homo sapiens (Human). Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn't transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Tumor Necrosis Factor Receptor Superfamily Member 10C; Antagonist Decoy Receptor for TRAIL/Apo-2L; Decoy TRAIL Receptor Without Death Domain; Decoy Receptor 1; DcR1; Lymphocyte Inhibitor of TRAIL; TNF-Related Apoptosis-Inducing Ligand Receptor 3; TRAIL Receptor 3; TRAIL-R3; TRAIL Receptor Without an Intracellular Domain; CD263; TNFRSF10C; DCR1; LIT; TRAILR3; TRID |
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| Gene, Accession, CAS # | TNFRSF10C, UniProt: O14798 |
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| Catalog # | RPC26942 |
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| Price | |
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| Order / More Info | Recombinant Mouse C-C motif chemokine 12 protein (Ccl12) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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