产品详情 |
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Antigenic Specificity | gamma-ENaC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | lyophilized |
Applications | Immunohistochemistry: 1:300 - 1:2000, Western Blot: 1:300-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | gamma-ENaC Polyclonal Antibody. Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. Heterotetramer of two alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2. Apical cell membrane; Multi-pass membrane protein. Phosphorylated on serine and threonine residues. Defects in SCNN1G are a cause of Liddle syndrome. It is an autosomal dominant disorder characterized by |
Immunogen | n/a |
Other Names | Amiloride-sensitive sodium channel subunit gamma (SCNN1G, SCNEG), Epithelial Na(+) channel subunit gamma, Gamma-ENaC, Gamma-NaCH, PHA1, ENaCg, SCNEG, |
Gene, Accession # | Entrez: 6340; Uniprot: P51170 |
Catalog # | OSR00095W |
Price | |
Order / More Info | gamma-ENaC Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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