产品名称 gamma-ENaC Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-51073
产品价格 现货询价,电话:010-67529703
产品规格 100 µl
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic Specificitygamma-ENaC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size100 µl
Concentrationn/a
ApplicationsELISA: 1:20,000, Western Blot: 1:500-1:2000
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Descriptiongamma-ENaC Polyclonal Antibody. Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. Heterotetramer of two alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2. Apical cell membrane; Multi-pass membrane protein. Phosphorylated on serine and threonine residues. Defects in SCNN1G are a cause of Liddle syndrome. It is an autosomal dominant disorder characterized by
Immunogenn/a
Other NamesSCNN1G, Amiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, ENaCG, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG
Gene, Accession #Entrez: 20278, 24768, 6340; Uniprot: P37091, P51170, Q9WU39
Catalog #PA5-51073
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Product Specific Referencesn/a
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