| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | PXR |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry: 5 µg/mL, Western Blot: 0.2-1 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PXR Polyclonal Antibody. This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. |
|---|
| Immunogen | n/a |
|---|
| Other Names | Nuclear receptor subfamily 1, group I member 2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR |
|---|
| Gene, Accession # | Entrez: 8856; Uniprot: O75469 |
|---|
| Catalog # | PA5-41170 |
|---|
| Price | |
|---|
| Order / More Info | PXR Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|