| 产品详情 |
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| Antigenic Specificity | Synuclein alpha/beta |
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| Clone | Syn 202 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Synuclein alpha/beta Monoclonal Antibody (Syn 202). Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system o |
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| Immunogen | n/a |
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| Other Names | Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, PARK1, PARK4, PD1, alpha-synuclein, non A-beta component of AD amyloid, synuclein alpha-140, SNCA, SNCB, alpha-synuclein, beta-synuclein |
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| Gene, Accession # | Entrez: 104069, 20617, 29219, 6620, 6622; Uniprot: O55042, P37377, P37840, Q16143, Q91ZZ3 |
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| Catalog # | 32-8200 |
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| Price | |
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| Order / More Info | Synuclein alpha/beta Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12388586 |
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