| 产品详情 |
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| Antigenic Specificity | SYT10 |
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| Clone | S269-73 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:400, Immunofluorescence: 1:400, Immunohistochemistry (PFA fixed): 1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SYT10 Monoclonal Antibody (S269-73). SYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis. |
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| Immunogen | n/a |
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| Other Names | SYT10, SYT-10, Synaptotagmin 10, Synaptotagmin X, SytX, P65, SVP65, DKFZp781D2042, SYT |
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| Gene, Accession # | Entrez: 341359, 54526, 60567; Uniprot: O08625, Q6XYQ8, Q9R0N4 |
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| Catalog # | MA5-27591 |
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| Price | |
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| Order / More Info | SYT10 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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