| 产品详情 |
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| Antigenic Specificity | RIPK-1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, FCM, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RIPK-1 Polyclonal Antibody. • Target Background: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critic |
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| Immunogen | KLH conjugated synthetic peptide derived from human RIPK-1/RIP. Immunogen Range: 600-650/671 |
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| Other Names | RIP; RIP1; Receptor-interacting serine/threonine-protein kinase 1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1; Serine/threonine-protein kinase RIP; RIPK1 |
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| Gene, Accession # | Gene ID: 8737, SwissProt: Q13546 |
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| Catalog # | bs-5805R |
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| Price | |
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| Order / More Info | RIPK-1 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Luo, Yuhao, et al. (2014) Tumour Biol. 1-9. PubMed: 25487618 |
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