| 产品详情 |
| Edit |   |
| Antigenic Specificity | Complement C4c |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 50 ug |
| Concentration | n/a |
| Applications | ELISA, IHC-Fr, IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse monoclonal to Complement C4c. Recognizes complement component 4c (C4c). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. iC4b is further degraded into the inactive fragments C4d and C4c. C4c consists of two a-chain fragments, alpha 4 (13 kD) and alpha 3 (25 kD) linked to a beta chain through disulphide bridges and a gamma chain. It is expressed in the blood plasma. Binds both C4c and C4 and so is not suitable for all ELISA applications. |
| Immunogen | Complement C4c antibody was raised against purified human C4c. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | orb137252 |
| Price | |
| Order / More Info | Complement C4c Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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