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| Product Name | Recombinant Human Protein phosphatase 1 regulatory subunit 15A (PPP1R15A), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 71.1kDa. Partial: 40-674aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116 homolog |
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| Gene, Accession, CAS # | PPP1R15A, UniProt: O75807 |
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| Catalog # | RPC24888 |
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| Price | |
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| Order / More Info | Recombinant Human Protein phosphatase 1 regulatory subunit 15A (PPP1R15A), partial from BIOMATIK |
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| Product Specific References | n/a |
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