| 产品详情 |
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| Product Name | Recombinant Human Protein-tyrosine phosphatase mitochondrial 1 (PTPMT1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 35.9kDa. Full Length of Mature Protein: 28-201aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the mbrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | PTEN-like phosphatasePhosphoinositide lipid phosphataseProtein-tyrosine phosphatase mitochondrial 1 (EC:3.1.3.16, EC:3.1.3.48) |
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| Gene, Accession, CAS # | PTPMT1, UniProt: Q8WUK0 |
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| Catalog # | RPC23316 |
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| Order / More Info | Recombinant Human Protein-tyrosine phosphatase mitochondrial 1 (PTPMT1) from BIOMATIK |
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| Product Specific References | n/a |
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