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| Product Name | CytoSelect 96-well Collagen Cell Invasion Assay, Fluorometric |
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| Description | Background: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the significant morbidity and mortality of cancers. Invasiveness requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Metastatic cells produce many proteolytic enzymes (e.g. lysosomal hydrolysates, collagenases, plasminogen activators) while the expression of certain cell surface protease receptors is also increa |
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| Size | 96 assays |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168013 |
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| Order / More Info | CytoSelect 96-well Collagen Cell Invasion Assay, Fluorometric from MYBIOSOURCE INC. |
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| Product Specific References | 1. Erkell, L. J., Schirrmacher, V. (1988) Cancer Res 48, 6933-6937.2. Montgomery, A. M. P., De Clerck, Y. A., Langley, K. E., Reisfeld, R. A., Mueller, B. M. (1993) Cancer Res 53,693-700.3. Monsky, W. L., Lin, C. Y., Aoyama, A., Kelly, T., Akiyama, S. K., Mueller, S. C., Chen, W. T. (1994) Cancer Res 54,5702-5710.1. Ishiba, T. e. al. (2014). Periostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion. Sci Rep. 4:7069.2. Ziemann, A. et al. (2013). CRN2 enhances the invasiveness of glioblastoma cells. Neuro Oncology 10.1093/neuonc/nos388.3. Liu, X. et al. (2013). Antiproliferative, antiinvasive, and proapoptotic activity of folate receptor alpha-targeted liposomal doxorubicin in nonfunctional pituitary adenoma cells. Endocrinology 154:1414-1423.4. Ziemann, A. et al. (2013). CRN2 enhances the invasiveness of glioblastoma cells. Neuro Oncology 10.1093/neuonc/nos388. |
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