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Product Name | 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide |
Description | Purity >98%. 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide is a sulfide-like inhibitor of phosphodiesterase 7 (PDE7; IC50 = 2.1 µM). It is selective for PDE7A, producing only 10-11% inhibition of PDE3A, PDE4D, and PDE4B at 10 µM. It also has no antioxidant activity or inhibitory activity against a panel of protein kinases. Sulfide-like PDE7 inhibitors derived from 2-acetamidophenyl 5-chloro-2-nitrophenyl sulfide have cytoprotective and anti-inflammatory effects on SH-SY5Y neuroblastoma cells without action in a surrogate emesis mouse model. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-[2-[(5-chloro-2-nitrophenyl)thio]phenyl]-acetamide, 2'-(5-chloro-2-nitrophenylthio)-Acetanilide |
Gene, Accession, CAS # | CAS: 107522-19-0 |
Catalog # | LS-H5961 |
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Order / More Info | 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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