| 产品详情 |
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| Product Name | Fura-FF AM |
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| Description | Purity >90%. Fura-FF AM is a cell-permeable acetoxymethyl ester of the fluorescence calcium indicator fura-FF (potassium salt) . As fura-FF AM enters cells, it is hydrolyzed by intracellular esterases to produce fura-FF. Fura-FF is a difluorinated derivative of the calcium indicator fura-2 . Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation. Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd (calcium) = 6 and 0.14 µM, respectively). However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presence of a high calcium concentration. Low affinity calcium dyes, including fura-FF, are preferred for studying compartments with high concentrations of calcium, such as mitochondria, or in cell systems that have relatively low calcium buffering capacities, such as neuronal dendrites and spines. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[6-[bis [2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-[2-[6-[bis [2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-2,3-difluorophenoxy]ethoxy]-2-benzofuranyl]-5-oxazolecarboxylic acid(acetyloxy)methyl ester, Fura-FF Acetoxymethyl ester |
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| Gene, Accession, CAS # | CAS: 348079-12-9 |
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| Catalog # | LS-H7868 |
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| Order / More Info | Fura-FF AM from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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