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Product Name | Furin Inhibitor I |
Description | Purity >95%. Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi/trans-Golgi secretory pathway. Furin inhibitor I is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.0 nM), SPC4/PACE4 (Ki = 3.6 nM), SPC6/PC5/PC6, and SPC7/LPC/PC7/PC8 (Ki = 0.12 nM). Because furin activates viral glycoproteins, this inhibitor is a useful antiviral agent. In addition, it inhibits furin-dependent pro-MMP-2 activation in mononuclear inflammatory cells. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N2 -(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-L-lysinamide, Decanoyl-Arg-Val-Lys-Arg-CMK |
Gene, Accession, CAS # | CAS: 150113-99-8 |
Catalog # | LS-H7873 |
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Order / More Info | Furin Inhibitor I from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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