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| Product Name | SMAD Family Member 4 (SMAD4) (AA 1-552) protein (His tag) |
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| Description | SMAD4 is part of the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription acts as a tumor suppressor. SMAD4 is a target molecule for functional inactivation in cervical cancer. SMAD4 is an important biomarker for malignant transformation atakes part in inducing apoptosis by modulating Bcl-2/Bax balance Synonyms: JIP, DPC4, MADH4, SMAD-4, DPC-4, MADH-4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, SMAD 4, hSMAD4, Deletion target in pancreatic carcinoma 4, SMAD4, SMAD family member 4 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | smad4|DPC4|JIP|MADH4|MYHRS|AW743858|D18Wsu70e|Madh4|XSmad4alpha|Xsmad4|dpc4|jip|madh4|xsmad4a |
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| Gene, Accession, CAS # | Gene ID: 4089 |
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| Catalog # | ABIN807003 |
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| Order / More Info | SMAD Family Member 4 (SMAD4) (AA 1-552) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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