| 产品详情 |
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| Product Name | ST-034307 |
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| Description | Purity >98% by NMR, TLC. ST-034307 is a novel selective adenylyl cyclase 1 (AC1) inhibitor, IC50=2.3 uM. Inhibits calcium2+-stimulated cAMP accumulation in HEK cells stably transfected with AC1. It was also shown to inhibit AC1 stimulated by forskolin- and Gas-coupled receptors in HEK-AC1 cells. It enhanced u-opioid receptor-mediated inhibition of AC1 but it blocked heterologous sensitization of AC1 caused by chronic u-opioid receptor activation. Displays analgesic properties in a mouse model of inflammatory pain. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-Chloro-2-(trichloromethyl)-4H-1-benzopyran-4-one |
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| Gene, Accession, CAS # | CAS: 133406-29-8 |
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| Catalog # | LS-H14857 |
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| Order / More Info | ST-034307 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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