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Product Name | L-Phenylephrine |
Description | Purity >98%. L-Phenylephrine is an adrenergic Alpha1A receptor agonist (Ki = 1.4 µM) that demonstrates selectivity against the Alpha1B and Alpha1C receptor subtypes (Ki s = 23.9 and 47.8 µM, respectively). By stimulating adrenergic Alpha1 receptors, L-phenylephrine can induce aortic smooth muscle contractions, although reported relative affinity and potency values in rabbit are 5-fold weaker compared to that of L-norepinephrine. This compound is frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents. Because L-phenylephrine acts on adrenergic Alpha1 receptors in the arterioles of the nasal mucosa to produce constriction, it has been examined clinically as an oral decongestant. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 3-hydroxy-aR-[(methylamino)methyl]-benzenemethanol, (R)-(-)-Phenylephrine |
Gene, Accession, CAS # | CAS: 59-42-7 |
Catalog # | LS-H8526 |
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Order / More Info | L-Phenylephrine from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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