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| Product Name | Human LTA / TNF Beta Protein (Recombinant) |
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| Description | Purity >95% by SDS-PAGE, MW: 18.6 kDa (SDS-PAGE). TNF is secreted by macrophages, monocytes, neutrophils, T-cells, NK-cells following their stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-alpha while CD8 cells secrete little or no TNF-alpha. The synthesis of TNF-alpha is induced by many different stimuli including interferons, IL2, GM-CSF. TNF-Beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands, and signals through TNFR1 and TNFR2. TNF-Beta is produced by activated T and B lymphocytes, and has similar activities to TNF-a. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. Recombinant Human TNF-Beta produced in E. coli is is a glycosylated polypeptide chain of 172 amino acids. A fully biologically active molecule,rhTNF-Beta has a molecular mass of 18.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LTA, Lymphotoxin-alpha, LT-alpha, TNFSF1, TNF-beta, TNFB, Tumor necrosis factor beta, LT, TNF Beta |
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| Gene, Accession, CAS # | LTA, Gene ID: 4049 |
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| Catalog # | LS-G27029 |
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| Order / More Info | Human LTA / TNF Beta Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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