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| Product Name | Urocortin III (human) (trifluoroacetate salt) |
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| Description | A neuropeptide hormone; selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively); stimulates cAMP production in CHO cells expressing rat CRF2α and mouse CRF2β (EC50s = 0.16 and 0.12 nM, respectively); co-released with insulin to potentiate glucose-stimulated somatostatin release in vitro in human pancreatic β-cells; reduces food intake in a dose- and time-dependent manner in mice (MED = 0.3 nmol/animal); increases swimming time in a forced swim test in mice, indicating antidepressant-like activity |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | anti-depressant CRF-2α 2β 1 357952-09-1 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 24748-1 |
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| Order / More Info | Urocortin III (human) (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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