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| Product Name | 680C91 |
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| Description | Purity >98% by NMR, TLC. 680C91 is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM) Displays no activity against indoleamine 2,3-dioxygenase, MAO-A and B and does not effect serotonin uptake. Elevates CSF tryptophan by up to 260% and CSF serotonin by 170% of basal. TDO inhibition by 680C91 in glioma cells blocked the release of kynurenine, an endogenous tumor promoting AHR ligand. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole |
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| Gene, Accession, CAS # | CAS: 163239-22-3 |
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| Catalog # | LS-H14569 |
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| Order / More Info | 680C91 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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