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| Product Name | PPME1, 1-386aa, Human, His tag, E Coli |
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| Description | MW: 44.4 kDa (406aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. PPME1, also known protein phosphatase methylesterase-1 (PME1), catalyzes the demethylation and inactivation of protein phosphatase (PP2A), which is a multimeric phosphoserine/ threonine protein phosphatase associated with growth inhibition and cell cycle arrest. It can demethylate PP2A catalytic subunit in vitro and okadaic acid treatment is capable of inhibiting this reaction. It is conserved from yeast to human and contains |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Protein phosphatase methylesterase 1; FLJ22226; PME-1] |
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| Gene, Accession, CAS # | PPME1, Gene ID: 51400, Accession: NP_057231 |
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| Catalog # | MBS204278 |
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| Order / More Info | PPME1, 1-386aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Ogris E. et al. (1999) J. Biol. Chem. 274: 14382-14391.; Gagnon S.N. et al. (2002) Biochem. J. 368:263-271. |
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