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| Product Name | Amyloid-β (17-42) Peptide (human) (trifluoroacetate salt) |
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| Description | A 26-residue fragment of the Aβ protein; formed via post-translational processing of APP by α- and γ-secretases; has been found in postmortem cerebral cortex from patients with Alzheimer's disease that have diffuse amyloid plaques and in cerebellar preamyloid lesions in patients with Down's syndrome; forms amorphous aggregates in vitro that bind less thioflavin T than Aβ (1-40) and Aβ (1-42); is cytotoxic to SH-SY5Y and IMR-32 cells in a concentration-dependent manner and induces cleavage of caspase-3 and PARP in SH-SY5Y cells at 20 µM |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Aβ (17-42)|LVFFAEDVGSNKGAIIGLMVGGVVIA |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 27415-500 |
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| Order / More Info | Amyloid-β (17-42) Peptide (human) (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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