| 产品详情 |
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| Antigenic Specificity | Lamin B2 |
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| Clone | E-3 |
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| Host Species | Mouse |
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| Reactive Species | chicken, human, mouse, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 10 µg/mL, Immunoprecipitation: 5 µg, Western Blot: 3.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Lamin B2 Monoclonal Antibody (E-3). Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial |
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| Immunogen | n/a |
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| Other Names | LAMB2, LMN2, lamin-B2 |
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| Gene, Accession # | Entrez: 16907, 299625, 396222, 84823; Uniprot: P14732, P21619, Q03252 |
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| Catalog # | 33-2100 |
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| Price | |
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| Order / More Info | Lamin B2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11590170, 12736269, 15958386, 16103124, 21842415, 22308344, 23650370, 24672053, 25312645, 26785729, 26837579 |
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