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Product Name | Recombinant Bovine RISC-loading complex subunit TARBP2 (TARBP2) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 45.8kDa. Full Length: 1-366aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Bos taurus (Bovine). Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | n/a |
Gene, Accession, CAS # | TARBP2, UniProt: Q0IIG6 |
Catalog # | RPC25952 |
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Order / More Info | Recombinant Bovine RISC-loading complex subunit TARBP2 (TARBP2) from BIOMATIK |
Product Specific References | n/a |
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