| 产品详情 |
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| Product Name | Epothilone B |
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| Description | Microtubule stabilization agent that promotes tubulin polymerization and induces G2-M cell cycle arrest (EC50 = 32 nM in HeLa cells). Inhibits proliferation of human carcinoma cell lines in vitro, including MDR cells overexpressing the P-glycoprotein efflux pump. Exhibits potent cytotoxicity in MCF-7 and A549 cells (EC50 values are 0.3 and 2.7 nM respectively). Inhibits growth of HCT-15 tumors in mice in vivo. Purity 98%. MW (observed): 507.68 |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione. Patupilone |
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| Gene, Accession, CAS # | CAS: 152044-54-7 |
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| Catalog # | 3502/100U |
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| Price | |
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| Order / More Info | Epothilone B from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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