| 产品详情 |
| Edit |   |
|---|
| Product Name | VX 745 |
|---|
| Description | Highly potent and selective p38α inhibitor (IC50 = 10 nM). Also blocks TNFα production in LPS-stimulated HWB in vitro (IC50 = 177 nM). Displays 1000-fold selectivity over closely related kinases, including ERK1, MK2 and JNK1-3. Purity 98%. MW (observed): 436.26 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 5-(2,6-Dichlorophenyl)-2-[2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one |
|---|
| Gene, Accession, CAS # | CAS: 209410-46-8 |
|---|
| Catalog # | 3915/10 |
|---|
| Price | |
|---|
| Order / More Info | VX 745 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 24244164 |
|---|
| 产品资料 |
|
|