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| Product Name | Recombinant Human BMP-4 (Animal-Free) |
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| Description | BMP-4 is a member of the bone morphogenetic protein (BMP) family of cytokines, which belong to the transforming growth factor beta (TGF-β) superfamily. BMP-4 plays a crucial function in the chondrogenic and osteogenic differentiation of mesenchymal stem cells as well as in the maintenance of adult cartilage and bone. Binding of BMP-4 to the BMPR-I/BMPR-II receptor complex was reported to activate several signaling pathways, such as the Smad, the MAPK, the PI3K/Akt, and the Wnt pathways, which are involved in bone formation, cell proliferation, and cell differentiation. Genetic defects in BMP-4 have been associated with microphthalmia and orofacial cleft. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | Bone morphogenetic protein 4 (BMP4), Bone morphogenetic protein 2B (BMP-2B) |
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| Gene, Accession, CAS # | Gene ID: 652 |
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| Catalog # | 710002 |
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| Order / More Info | Recombinant Human BMP-4 (Animal-Free) from BIOLEGEND |
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| Product Specific References | n/a |
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