| 产品详情 |
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| Product Name | EX 527 |
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| Description | Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Enhances p53 acetylation in response to DNA damaging agents. Purity 98%. MW (observed): 248.71 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
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| Gene, Accession, CAS # | CAS: 49843-98-3 |
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| Catalog # | 2780/1 |
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| Price | |
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| Order / More Info | EX 527 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19295512, 19690166, 20810901, 21245135, 21321203, 21799305, 21947282, 22146233, 23070521, 23299244, 23382074, 24040162, 24454277, 24549276, 24850427, 25128742, 25186738, 25250818, 25319116, 25681462, 25918343, 25979359, 26594146, 27639555, 28553103 |
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