产品详情 |
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Product Name | Neratinib |
Description | Cell-permeable. A second-generation inhibitor of the ErbB family of receptor kinases. Neratinib acts as an irreversible inhibitor of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER-2) tyrosine kinases by targeting a cysteine residue in the ATP-binding site of the receptor. It inhibits the proliferation of HER-2 overexpressing human breast cancer cell lines and EGFR-dependent cells in vitro. MW: 557.04. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | HKI-272 |
Gene, Accession, CAS # | CAS: 698387-09-6 |
Catalog # | 2023-25 |
Price | |
Order / More Info | Neratinib from BIOVISION, INC. |
Product Specific References | n/a |
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