| 产品详情 |
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| Product Name | Neratinib |
| Description | Cell-permeable. A second-generation inhibitor of the ErbB family of receptor kinases. Neratinib acts as an irreversible inhibitor of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER-2) tyrosine kinases by targeting a cysteine residue in the ATP-binding site of the receptor. It inhibits the proliferation of HER-2 overexpressing human breast cancer cell lines and EGFR-dependent cells in vitro. MW: 557.04. Purity ≥98% by HPLC |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | HKI-272 |
| Gene, Accession, CAS # | CAS: 698387-09-6 |
| Catalog # | 2023-25 |
| Price | |
| Order / More Info | Neratinib from BIOVISION, INC. |
| Product Specific References | n/a |
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