| 产品详情 |
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| Product Name | Mouse CSF-1 receptor Recombinant (CSF-1R) |
| Description | MW: 109,179 Da. Purity >98%, as determined by SDS-PAGE and HPLC. The CSF-1R is a member of the type III receptor tyrosine kinase family that includes other structurally related kinases such as Kit and platelet-derived growth factor (PDGF) -R. CSF-1 binding to the CSF-1R triggers dimerization, autophosphorylation, and activation of key signaling pathways including the PI-3 kinase/Akt and mitogen- activated protein kinase (MAPK) pathways. |
| Size | 0.02 mg, 0.1 mg, 0.5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [Mouse CSF-1 receptor Recombinant; CSF1; MCSFR; csf-1; csf-1r] |
| Gene, Accession, CAS # | MCSFR, Gene ID: 12978, Accession: NP_001032948.2 |
| Catalog # | MBS553278 |
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| Order / More Info | Mouse CSF-1 receptor Recombinant (CSF-1R) from MYBIOSOURCE INC. |
| Product Specific References | • macrophage proliferation is regulated through CSF-1 receptor tyrosines 544, 559, and 807 .J. Biol. Chem., Apr 2012; 287: 13694 - 13704. • therapeutic applications of macrophage colony-stimulating factor-1 (csf-1) and antagonists of CSF-1 receptor (csf-1r) signaling .Blood, Feb 2012; 119: 1810 - 1820. • autocrine csf-1 and CSF-1 receptor coexpression promotes renal cell carcinoma growth .Cancer Res., Jan 2012; 72: 187 - 200. • a CSF-1 receptor phosphotyrosine 559 signaling p |
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