| 产品详情 |
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| Antigenic Specificity | APOBEC3H |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APOBEC3H Polyclonal Antibody. DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. The A3H-var/haplotype 2 exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together ex |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 164668; Uniprot: Q6NTF7 |
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| Catalog # | PA5-68166 |
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| Price | |
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| Order / More Info | APOBEC3H Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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