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| Product Name | Recombinant Human HLA class II histocompatibility antigen, DRB1-12 beta chain protein |
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| Description | 31-266aa; Full Length. MW: 31.2kD. Purity >90% as determined by SDS-PAGE. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents th on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and ot |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [MHC class II antigen DRB1*12; DR-12; DR12] |
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| Gene, Accession, CAS # | HLA-DRB1, Gene ID: 3123, Accession: Q95IE3.1 |
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| Catalog # | MBS1265582 |
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| Order / More Info | Recombinant Human HLA class II histocompatibility antigen, DRB1-12 beta chain protein from MYBIOSOURCE INC. |
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| Product Specific References | Sequence of a new DR12 allele with two silent mutations that affect PCR-SSP typing.Zanone R., Bettens F., Tiercy J.M.Tissue Antigens 59:165-167(2002) Identification of a novel HLA-DRB1*12 allele (DRB1*1210) in the Korean population.Kim E., Lee E.J., Lim Y.H., Lee J.Y., Koh I.S., Kimm K., Ji G.E., Kwack K.Tissue Antigens 64:518-519(2004) Identification of a novel HLA-DRB1 allele, HLA-DRB1*1217, in a Korean individual.Park M.H., Kim Y., Lee J.Y.Tissue Antigens 73:627-628(2009) Ancient haplotypes o |
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