| 产品详情 |
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| Product Name | TIGAR, human recombinant |
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| Description | TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant human TIGAR expressed in E. coli is a 29.9 kDa protein containing 269 amino-acid residues. MW: 29.9 kDa. Purity ≥95% |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | TP53-induced glycolysis and apoptosis regulator (TIGAR) |
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| Gene, Accession, CAS # | TIGAR, Gene ID: 57103, Accession: Q9NQ88 |
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| Catalog # | 7217-50 |
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| Order / More Info | TIGAR, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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