| 产品详情 |
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| Product Name | Ro 31-8220 methanesulfonate |
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| Description | Cell-permeable. A potent bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively). It inhibits protein kinase A (PKA) (IC50 = 0.9 µM) and calcium/calmodulin kinase II (IC50 = 17 µM) at much higher concentrations. Also inhibits glycogen synthase kinase-3 (GSK-3) (IC50 = 6.8 nM). MW: 553.65. Purity ≥98% by NMR |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide methanesulfonate; Bisindolylmaleimide IX methanesulfonate; BIM IX |
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| Gene, Accession, CAS # | CAS: 138489-18-6 |
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| Catalog # | 1946-5 |
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| Order / More Info | Ro 31-8220 methanesulfonate from BIOVISION, INC. |
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| Product Specific References | n/a |
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