| 产品详情 |
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| Antigenic Specificity | Human Kindlin 1 |
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| Clone | 8I8M0 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | FC, ICC, IF, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human Kindlin 1 monoclonal antibody for FC, ICC, IF, WB. Kindlin 1 is a member of the kindlin family of focal adhesion proteins and contains a FERM domain and pleckstrin homology domain. It is involved in integrin signaling, linkage of the cytoskeleton to the extracellular matrix, and cell adhesion. It is most often expressed in epithelial cells. When kindlin 1 is coexpressed with talin it helps to activate ITGA2B. It is required for keratinocyte proliferation, polarization of basal keratinocytes in the skin, and for normal cell shape. Mutations in kindlin 1 have been linked to Kindler syndrome, a recessive skin disorder involving blistering, photosensitivity, poikiloderma, and atrophy. |
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| Immunogen | Protein corresponding to Human FERMT1 (aa 200-409) |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 55612, UniProt: Q9BQL6 |
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| Catalog # | CABT-L1299 |
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| Price | |
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| Order / More Info | Human Kindlin 1 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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