| 产品详情 |
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| Product Name | MPEP hydrochloride |
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| Description | MW: 229.71. Purity ≥98% by HPLC. MPEP hydrochloride is a highly selective and potent non-competitive antagonist at the mGlu5 (metabotropic glutamate receptor subtype 5) receptor subtype (IC50 = 36 nM). It is a positive allosteric modulator at mGlu4. MPEP hydrochloride reduces DHPG (S-3; 5-dihydroxyphenylglycine)-induced excitations but not the excitations induced by AMPA (-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). In vivo studies show it reverses mechanical hyperalgesia in the infl |
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| Size | 10 mg, 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [2-Methyl-6- (phenylethynyl) pyridine hydrochloride] |
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| Gene, Accession, CAS # | CAS: 219911-35-0 |
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| Catalog # | MBS846294 |
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| Price | |
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| Order / More Info | MPEP hydrochloride from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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