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Product Name | MPEP hydrochloride |
Description | MPEP hydrochloride is a highly selective and potent non-competitive antagonist at the mGlu5 (metabotropic glutamate receptor subtype 5) receptor subtype (IC50 = 36 nM). It is a positive allosteric modulator at mGlu4. MPEP hydrochloride reduces DHPG (S-3, 5-dihydroxyphenylglycine)-induced excitations but not the excitations induced by AMPA (-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). In vivo studies show it reverses mechanical hyperalgesia in the inflamed rat hind paw. MW: 229.71. Purity ≥98% by HPLC |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
Gene, Accession, CAS # | CAS: 219911-35-0 |
Catalog # | B1151-50 |
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Order / More Info | MPEP hydrochloride from BIOVISION, INC. |
Product Specific References | n/a |
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