| 产品详情 |
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| Product Name | MK-0752 |
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| Description | MK-0752 is a potent and reversible inhibitor of γ-secretase, reducing the cleavage of APP to Aβ40 in human neuroblastoma SH-SY5Y cells (IC50 = 5 nM). Through its effects on the Notch pathway, MK-0752 reduces the number of breast cancer stem cells in tumorgrafts, enhancing the efficacy of the chemotherapy drug docetaxel (Cat. No. 2232) in mice with breast cancer tumors. MW: 442.9. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[4-(4-chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]propanoic acid |
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| Gene, Accession, CAS # | CAS: 471905-41-6 |
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| Catalog # | B1980-5 |
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| Price | |
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| Order / More Info | MK-0752 from BIOVISION, INC. |
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| Product Specific References | n/a |
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