| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | APS |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: 1:500 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | APS Polyclonal Antibody. APS (adapter protein with Pleckstrin homology and Src homology 2 domains) a member of the Lnk family, is an adaptor protein that is involved in B-cell signaling, insulin signaling, cytoskeletal reorganization. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B-cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK-STAT pathway in collaboration with c-Cbl. It is located in the cytoplasm in pre-PDGF (platelet derived growth factor) stimulated cells and localizes to the plasma membrane and peripheral regions upon PDGF stimulation. This protein is expressed in B-cells and mast cells when detected in haematopoietic cell lines yet is also |
|---|
| Immunogen | n/a |
|---|
| Other Names | Alpha-1-antiproteinase S, Alpha-1-antitrypsin, Alpha-1-proteinase inhibitor |
|---|
| Gene, Accession # | Entrez: 23921; Uniprot: Q9JID9 |
|---|
| Catalog # | PA1-1062 |
|---|
| Price | |
|---|
| Order / More Info | APS Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|