| 产品详情 |
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| Product Name | PX-478 hydrochloride |
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| Description | PX-478 hydrochloride is an inhibitor of HIF-1α (IC50 of 20-30 µM) with potential antineoplastic activity. PX-478 inhibits HIF-1alpha protein levels and transactivation in a variety of cancer cell lines. The inhibitory effect of PX-478 on HIF-1alpha levels is primarily due to its inhibition of translation because HIF-1alpha translation continues in hypoxia when translation of most proteins is decreased. MW: 394.11. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (S)-4-(2-amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)aniline oxide dihydrochloride |
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| Gene, Accession, CAS # | CAS: 685898-44-6 |
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| Catalog # | B1033-5 |
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| Order / More Info | PX-478 hydrochloride from BIOVISION, INC. |
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| Product Specific References | n/a |
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