| 产品详情 |
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| Antigenic Specificity | CMKLR1 |
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| Clone | BZ332 |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CMKLR1 Monoclonal Antibody (BZ332), FITC. Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). {ECO:00 |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 1240; Uniprot: Q99788 |
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| Catalog # | MA5-28098 |
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| Price | |
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| Order / More Info | CMKLR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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