产品详情 |
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Product Name | TC 2559 difumarate |
Description | Subtype-selective partial agonist for α4β2 nicotinic acetylcholine receptors (EC50 values are 0.18, 12.5, 14.0, > 30, > 100 and > 100 μM for α4β2, α4β4, α2β4, α3β4, α3β2 and α7 receptor subtypes respectively). Displays selectivity for (α4)2(β2)3 receptor stoichiometry and enhanced CNS-PNS selectivity ratio. Attenuates scopolamine-induced cognitive deficits in a step-through passive avoidance task. Purity 98%. MW (observed): 438.43 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-(5-ethoxy-3-pyridinyl)-N-methyl-(3E)-3-buten-1-amine difumarate |
Gene, Accession, CAS # | CAS: 212332-35-9 |
Catalog # | 2737/50 |
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Order / More Info | TC 2559 difumarate from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19139119, 29587798 |
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